Nguyen Minh Nam

Dr. Nguyen Minh Nam graduated in Biotechnology from Nong Lam University Ho Chi Minh City (Vietnam) in 2006 and had been awarded for his master degree in 2013 and Ph.D degree in 2016 by Kyung Hee University, Seoul, Korea in Biomedicine. After receiving Ph.D degree, he services as a Research Professor at the same Kyung Hee University (2016 – 2017) and then moved to Yale University, United State (2017 – 2019) to work in Biomedical research. He has an extensive academic background in biological sciences combined with strong practical work experience in basic and translational research, especially in Cancer biology fields. By using Bigdata analysis and Machine learning tools, he established several novel prognostic gene signatures for diverse Cancer such as colorectal cancer, breast cancer, ovarian cancer, and glioma which would help to develop adjuvant therapeutic strategies for Personalized cancer treatment and provide a new insight to elucidate cancer heterogeneity in both genetic and epigenetic aspects. So, his study focuses on developing outcome prediction tools to select the right medication and the right time for the right patient. Furthermore, he also plans to identify the mechanism that governs therapy resistance and investigate the novel target for drug discovery to enhance the effect of cancer treatment and reduce side effects. He has been a reviewer of several journals, such as Journal of Pineal Research, Journal of Bone and Mineral Research, Scientific Report, Journal of Oncology, and Advances in Urology.

Qualifications

• Postdoc (Biomedicine): Yale School of Medicine, USA
• PhD (Biomedicine): School of Medicine, Kyung Hee University, Republic of Korea
• MSc (Biomedicine): School of Medicine, Kyung Hee University, Republic of Korea
• BSc (Biotechnology): Nong Lam University, HCMC, Vietnam

Honours, awards and grants

• The best doctoral thesis prize in the medical field among winter 2016 graduates. Kyung Hee University.
• BioAsia innovation 2016. BioAsia 2016 at HICC, Hyderabad, India. Feb, 2016
• Outstanding student research among all Vietnamese students in Korea in 2015.
• Best Research Award. Korean Society for Biochemistry and Molecular Biology, 2015. Seoul, Korea.
• The first prize at the 4th youth scientific technology conference for universities and colleges of Agriculture-Forest- Aquaculture in whole country 2009. Vietnam.

Key responsibilities

• Teaching
• Research

Teaching

• Cell & Molecular Biology
• Biochemistry
• Cancer biology

Research

• Cancer biology
• Translational medicine
• Precision Medicine
• System biology
• Molecular diagnostics

Professional engagement

• Apr 2017 – present: Posdoctoral associate, School of Medicine, Yale University.
• Apr 2016 – Mar 2017: Research Professor, School of Medicine, Kyung Hee University, Seoul, Korea
• Nov 2006 – Mar 2010: Lecturer, Nong Lam University Ho Chi Minh City, Viet Nam.

Publications

• Hoa Quynh Tran, Van Thai Than, Phuc Loi Luu, Declan Clarke, Hanh Ngoc Lam, Thanh Giang Tan Nguyen, Dinh Truong Nguyen, Phan Q. Duy, Dung Phung, Minh Nam Nguyen. A Novel Signature Predicts Recurrence Risk and Therapeutic Response in Breast Cancer Patients. Int J Cancer. 2021
• Phat Xuan Dinh, Minh Nam Nguyen, Hien The Nguyen, Vu Hoang Tran, Quy Dinh Tran, Kim Hoang Dang, Dai Tan Vo, Hien Thanh Le, Nam Thi Thu Nguyen, Toan Tat Nguyen, Duy Tien Do. PCV2 genotype and its co-pathogens in PRDC-affected pigs in Southern provinces of Vietnam. Archives of Virology. 166, 403-411, 2021. (co-first author)
• Gio Nguyen, Manh Tran, Quynh Hoa Tran, Minh Nam Nguyen. SLC10A1 Gene as a Potential Biomarker for Diagnosis and Prognosis of Hepatocellular Carcinoma. Free Radical Biology and Medicine. 2020, 59:S58-S59.
• Van Thai Than, Ha Thi Thanh Chan, Duc Viet Ly, Hoang Vu Dang, Minh Nam Nguyen Anh Duc Truong;. Bioinformatic identification and expression analysis of the chicken B cell lymphoma (BCL) gene. Genes & Genomics. 2019.
• Dinh-Truong Nguyen, Quynh Hoa Tran, Xuan The Hoang, Ngoc Huyen Vu, Kim Van Thi Le, Van Thai Than, Minh Nam Nguyen. Glyoxalase 2 correlates with redox signaling and enhances survival outcome in patients with hepatocellular carcinoma. Free Radical Biology and Medicine. 2018, 128, S71.
• Si Nguyen Thu Mai, Huyen Ngoc Vu, Xuan The Hoang, Van Thai Than, Trung Viet Nguyen, Minh Thon Le, Phuc-Loi Luu, Hoa Quynh Tran, Minh Nam Nguyen. Decreased mortality strongly correlated with the upregulation of BCR in breast cancer metastasis to bone. Annals of Oncology, Volume 29, Issue suppl_9, 1 November 2018.
• Izuchukwu Ibe, Adam Sahlstrom, Minh Nam Nguyen, Dieter Lindskog, Gary E Friedlaender, Francis Y Lee. Immuno-oncologic Approach to Musculoskeletal Tumors. Techniques in Orthopaedics. Volume 33, Number 3, September 2018, pp. 140-147(8).
• Tae Gyu Choi, Minh Nam Nguyen, Jieun Kim, Yong Hwa Jo, Miran Jang, Ngoc Ngo Yen Nguyen, Hyeong Rok Yun, Wonchae Choe, Insug Kang, Joohun Ha, Dean G Tang, Sung Soo Kim. Cyclophilin B induces chemoresistance by degrading wild type p53 via interaction with MDM2 in colorectal cancer. The Journal of pathology. 2018 Sep;246(1):115-126. (co-first author)
• Abel Matondo, Yong Hwa Jo, Muhammad Shahid, Tae Gyu Choi, Minh Nam Nguyen, Ngo Yen Ngoc Nguyen, Salima Akter, Insug Kang, Joohun Ha, Chi Hoon MAENG, Si-Young Kim, Ju-Seog Lee, Jayoung Kim, and Sung Soo Kim. The Prognostic 97 Chemoresponse Gene Signature in Ovarian Cancer. Scientific report. 2017; 7: 9689
• Muhammad Shahid, Tae Gyu Choi, Minh Nam Nguyen, Abel Matondo, Yong Hwa Jo, Ji Youn Yoo, Ngo Yen Ngoc Nguyen, Hyeong Rok Yun, Jieun Kim, Salima Akter, Insug Kang, Joohun Ha, Chi Hoon Maeng, Si-Young Kim, Ju-Seog Lee, Jayoung Kim, and Sung Soo Kim. An 8-Gene Signature for Prediction of Prognosis and Chemoresponse in Non-Small Cell Lung Cancer. Oncotarget, 2016 Nov 15.
• Ara Jo, Tae Gyu Choi, Yong Hwa Jo, Jyothi K. R., Minh Nam Nguyen, Jin-Hwan Kim, Sangbin Lim, Muhammad Shahid, Salima Akter, Seonmin Lee, Kyung Hye Lee, Weon Kim, Hyuck Cho, Juhie Lee, Kevan M. Shokat, Kyung-Sik Yoon, Insug Kang, Joohun Ha, Sung-Soo Kim. Inhibition of carbonyl reductase 1 safely improves the efficacy of doxorubicin in breast cancer treatment. Antioxid Redox Signal. 2016 Aug 5
• Muhammad Shahid, Kyoung Min Cho, Minh Nam Nguyen, Tae Gyu Choi, Yong Hwa Jo, Saurav Nath Aryal, Ji Youn Yoo, Hyeong Rok Yun, Jae Woong Lee, Young Gyu Eun, Ju-Seog Lee, Insug Kang, Joohun Ha, Hwi-Joong Yoon, Si-Young Kim, Sung Soo Kim. Prognostic value and their clinical implication of 89-gene signature in glioma. Oncotarget. 2016 Jun 13
• Minh Nam Nguyen. Reversing Hormone Therapy Resistance: A Novel Era of Epigenetic Therapy in Breast and Prostate Cancers. J Steroids Horm Sci 6:e116. (2015)
• Minh Nam Nguyen, Tae Gyu Choi, Dinh Truong Nguyen, Jin-Hwan Kim, Yong Hwa Jo, Muhammad Shahid, Salima Akter, Saurav Nath Aryal, Ji Youn Yoo, Yong-Joo Ahn, Kyoung Min Cho, Ju-Seog Lee, Wonchae Choe, Insug Kang, Joohun Ha, Sung Soo Kim. CRC-113 gene expression signature for predicting prognosis in patients with colorectal cancer. Oncotarget. 2015 Oct 13;6(31):31674-92.
• Minh Nam Nguyen. Gene Signature: A Guideline for Hormonal Therapy in Breast Cancer. J Steroids Hormon Sci 6:e115. (2015)
• Salima Akter, Tae Gyu Choi, Minh Nam Nguyen, Abel Matondo, Jin-Hwan Kim, Yong Hwa Jo, Ara Jo, Muhammad Shahid, Dae Young Jun, Ji Youn Yoo, Yen Ngoc Nguyen Ngo, Seong-Wook Seo, Liaquat Ali, Ju-Seog Lee, Kyung-Sik Yoon, Wonchae Choe, Insug Kang, Joohun Ha, Jayoung Kim, Sung Soo Kim. Prognostic Value of a 92-Probe Signature in Breast Cancer. Oncotarget. 2015 Jun 20;6(17):15662-80.
• K R Jyothi, Jagadish Beloor, Ara Jo, Minh Nam Nguyen, Tae Gyu Choi, Jin-Hwan Kim, Salima Akter, Sang-Kyung Lee, Chi Hoon Maeng, Hyung Hwan Baik, Insug Kang, Joohun Ha, Sung Soo Kim. Liver-targeted cyclosporine A encapsulated PLGA nanoparticles inhibit viral replication in HCV mouse model. Int J Nanomedicine. 2015 Jan 30;10:903-21.
• Amarjargal Dashdorj, Jyothi Kr, Sangbin Lim, Ara Jo, Minh Nam Nguyen, Joohun Ha, Kyung-Sik Yoon, Hyo Jong Kim, Jae-Hoon Park, Michael P Murphy, Sung Soo Kim. Mitochondria-targeted antioxidant MitoQ ameliorates experimental mouse colitis by suppressing NLRP3 inflammasome-mediated inflammatory cytokines. BMC Med. 2013 Aug 6; 11:178.
• Sangbin Lim, Ju Young Shin, Ara Jo, Jyothi K.R, Minh Nam Nguyen, Tae Gyu Choi, Jinhwan Kim, Jae-Hoon Park, Young Gyu Eun, Kyung-Sik Yoon, Joohun Ha, Sung Soo Kim. Carbonyl reductase 1 is an essential regulator of skeletal muscle differentiation and regeneration. Int J Biochem Cell Biol. 2013 Aug; 45(8):1784-93.